Saturday, August 02, 2008

Could a Pill Replace Exercise?

Scientists have shown that a drug improves endurance in mice
By Nikhil Swaminathan
Scinetific American

KNN: What will they think of next?

Good news for couch potatoes. There may be a pill that lets them watch their TV and get their exercise, too—without moving a muscle.

Scientists have found a drug that mimics the effects of a workout by, among other things, increasing the body's ability to burn fat.

The study shows the pill can also increase endurance; lab mice that took it ran more than 40 percent longer on a treadmill than their untreated peers.

"It's tricking the muscle into 'believing' it's been exercised daily," says Ronald Evans, a developmental biologist at the Salk Institute for Biological Studies, in La Jolla, Calif., and co-author of a study published in Cell. "It proves you can have a pharmacologic equivalent to exercise.

"In addition to supercharging stamina, the drug, called AICAR, may also be useful in treating debilitating muscular disorders such as muscular dystrophy as well as metabolic diseases such as diabetes, because it also appears to help the body use and remove sugar from the blood more effectively.

Researchers say that AICAR—which is in clinical trials to treat some heart ailments—in essence works by reprogramming muscle, switching it from sugar-burning, fast twitch muscle—which is better for speed and power—into fat-burning, slow-twitch muscle that does not tire as easily.

The key to this transformation is a protein called PPARdelta, which Evan's team previously showed could create so-called high-endurance "marathon mice" if it genetically engineered the animals were genetically engineered to make a lot of it. But, another experimental drug that targeted only PPARdelta had some metabolic benefits, including lowering fatty acids and blood sugar, but it only boosted endurance in mice that were running regularly.

See: Could a Pill Replace Exercise?

1 comment:

tifaeny said...

Hello my
Brotha's and Sista's
Love, Peace and Happiness
to you from the Palpitations in
my heart, Trulee

Boy ooh Boy
The Devil stay buisy!
M M Mmm

That's why I give weekly quizzes
to my children teaching them about his game. All the kids luv to play
Here is how they learn
See below their True or False
dealing with reality!

Question number one
they are asked?

What's the name of Mr. Slick
who has deceived the whole world
making (Spirits) believe that his way is the right way?

Know they are asked
What are some of the Visual things that are (funny) that the Devil does?

One child says,
smiling while laughing
Making people think pills R
My reply
I need more to the story?

The child replies
ooh he know how to make people forget how to think, move, eat, and drink with the chemicals he use
in pills! You know he like to
alter Human Minds!

Like making us think that chemicals R safe for (Our Souls)
and Minds!

I say Yay! Good job! Give me an
They all scream
& Death
True or False mommy?

Next question
Does he care about your senses?
Anyone may reply?

They all yell Nope!
He ain't got it N him!
as they laugh saying
when we get big to be adults
we going to Evaporate Him!

I say how u going to do that?

They reply
Our next generation is growing up with Common Sense, by then
everything we ingest will be
made by Righteous Beings
(Light) will always shine in
through Darkness

last sceene
called the Joke of the Day

If you were invited to a
"Comedy Show" in Heaven
would you laugh if someone
Pills, Pills
Kill, Kill, Kill
Yes or No

Me oh my
what is the Devil going to do
when all "The Kids"
Identify the Truth
and start to refuse his
Produce of Falsehood
With them telling their parents
No, No, No
"Yah" is Good, remember?

The End

Much internal Love